Holly Marie Combs & Shannen Doherty
Holly Marie Combs and Shannen Doherty are probably best known for their roles on the hit WB series Charmed, but their friendship goes far beyond that show. Doherty secured the role of Prue Halliwell in Charmed and invited her bestie to try out for the role of Piper. The pair’s obvious chemistry from their many years of friendship is one of the biggest reasons why Combs got the part! Unfortunately, there was some drama on set between Doherty and fellow co-star Alyssa Milano, which led to Doherty leaving the show. Despite that, she and Combs remained best friends and are a big part of each other’s lives. The pair recently met back up during a Charmed convention in 2023, and their love for each other was beyond obvious!