Penelope Cruz & Salma Hayek
Cruz and Hayek’s friendship was forged in fire, which is probably why their bond is as unbreakable as steel! The pair were already friends when their plane had to make an emergency landing while flying them to Mexico to film Bandidas in 2004. The pair became inseparable after surviving this near-death experience and developed one of the most adored friendships in Hollywood history. They even developed their own special pet names for each other, and the pair frequently posts on social media about their adventures together.