Steve Martin & Martin Short
Martin and Short have one of the longest friendships on this list- lasting nearly forty years! The pair met while filming 1986 hit Three Amigos! and became fast friends. Over the years, they’ve worked on other projects together, including their most recent Hulu film, Only Murders in the Building. As the decades passed, Martin and Short became integral parts of each other’s lives. The pair supported each other through major life events and even vacationed together. Martin spoke with PEOPLE about their friendship and said, “There’s just an ease between us. Sometimes, I’ll hang out with Marty, and I’ll realize I haven’t laughed that hard in two months. And that just feels great.”